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The Brain-Eating Amoeba

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  • The Brain-Eating Amoeba

    Wasn't sure wether to put this in Science or Health. It incorporates
    aspects of both. I found it to be an interesting read even though i'm not
    really that into biology.


    Brain-Eating Amoeba
    Thrives in
    Warm, Fresh
    Water



    The dangerous amoeba has killed three

    people this summer. Here's what you should

    know about it.


    • People can't be infected with the amoeba by swallowing contaminated water.
    • Ongoing heat and droughts could put more people at risk.
    • The organism travels from the nose to the brain.



    An image of Trophozoites of N. fowleri in brain
    tissue, stained.


    The brain-eating amoeba that killed three people this summer is an
    organism that thrives in warm fresh water and can be found in lakes,
    rivers, hot springs and soil, according to the Centers for Disease Control
    and Prevention.

    All three deaths this year occurred in the South: a 16-year-old girl in
    Florida, a 9-year-old boy in Virginia and a 20-year-old man in Louisiana.

    A brutal summer and drought make the conditions perfect for the amoeba.
    The threat of N. fowleri could potentially be elevated for weeks in some
    areas. According to the CDC, infections occur mainly in July, August and
    September.

    The microscopic amoeba, Naegleria fowleri, attacks anyone who has the
    misfortune of inhaling it. It enters first up the nose and then goes to the
    brain, usually killing its victims within two weeks.

    "Once forced up the nose, it can travel to the brain, where it digests brain
    cells," Jonathan Yoder, an epidemiologist at the Centers for Disease Control
    and Prevention, told Discovery News. "It's a very tragic disease that
    thankfully is very rare."

    Aside from its rarity, the amoeba "is not looking to prey upon human
    victims," he said. "They usually go after bacteria in water and soil."

    As single-celled organisms, amoebas do not even have brains. However,
    Naegleria species, including this disease-causing one, can transform
    themselves into three different basic "body" types.

    "This one-celled organism hunts and eats bacteria as an amoeba, swims
    around looking for a better environment as a flagellate, and then hunkers
    down and waits for good times as a cyst," said Simon Prochnik, a
    computational scientist at the U.S. Department of Energy’s Joint Genome

    Institute. "It is a very rare process to go from amoeba to flagellate like
    this."

    Prochnik, who sequenced the genome of a Naegleria species last year,
    explained that when environmental conditions are not favorable, the
    "stressed" amoeba can quickly grow two tails, transforming it into the
    flagellate. It can then swim and move around to a better spot, similar to
    the way that human sperm travel.

    To support these three body or "personality" types, as Prochnik calls them,
    the organism is packed with genes: 15,727 of them. To put that into
    perspective, humans have 23,000 protein-coding genes.

    Since the creature is so versatile, it can lurk in warm, moist places for
    extended periods. In the case of the first death from the disease earlier
    this summer -- a man from Louisiana who used a neti pot -- it's believed
    the organism was living in his home's water system. The CDC said the
    investigation into that death is ongoing, but the man may have put the
    infected tap water into his nose without boiling it first.

    Yoder said it is important to follow the directions included with neti pots,
    which look like teapots and are used to relieve sinus problems. The
    instructions usually mention that users should put distilled, boiled water in
    them and not just water right out of the tap.

    If users don't follow these instructions, there is a slim chance they too
    might get the disease caused by Naegleria fowleri, which is called primary
    amebic meningoencephalitis, or "PAM."

    According to CDC data, 32 cases -- all fatal -- occurred between 2001 and
    2010. From 1937 to 2007, there were 121 reported cases. Yoder knew of
    only one survivor, an individual who became infected in 1978.

    "The same treatment course provided then has been tried on others
    without success," he said.

    Diagnosing this disease is difficult. Yoder explained that associated
    symptoms, such as high fever, headache, and stiff neck, are present with
    bacterial and viral meningitis, so misdiagnoses are possible.

    The Florida Department of Health has issued warnings to prevent further
    deaths due to the disease.

    "During the hottest time of the summer, water in ponds, lakes, and rivers
    become very warm and there can be increases in the amounts of amoeba
    present," said Florida DOH spokesperson Christie Goss. "We advise
    everyone to be aware of the danger of swimming in such water, but
    especially of stirring up the sediment in shallow water or diving and
    swimming under water which can enable the amoeba to enter the nose and
    possibly infect the brain."

    Both the DOH and the CDC add that it may help to "hold your nose, or use
    nose plugs when jumping or diving into water."
    Much about N. fowleri remains a mystery. Anne Oplinger, a spokesperson
    for the National Institute of Allergy and Infectious Diseases, told Discovery
    News that she wasn't aware of any federally funded studies investigating
    the disease at present.

    Health officials at the CDC and elsewhere, however, are closely monitoring
    the cases, to detect any possible patterns or if the caseload might rise in
    future due to climate change or other possible contributing factors. So far,
    the number of PAM deaths this year falls within the annual national
    average.



    Brain-Eating Amoeba Thrives in Warm, Fresh Water : Discovery News




    Something to think about the next time you do wudu/audas. Joking of
    course. It is very rare, there is nothing to be worried about. Still very
    interesting.
    ---
    To advise others is an easy matter, the difficulty is accepting advice -- since it is bitter for those who follow their
    own inclinations and desires
    .


    -Imam al Ghazali
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