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What is it?
CF is an inherited condition affecting the glands that produce body fluids or secretions.
In CF, these secretions are stickier and thicker than normal. This hinders the functioning of important organs, such as the lungs and digestive system.
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What causes it?
The exact cause of CF is a single faulty gene found on chromosome 7, which controls salt and water movement in and out of cells within the body. To develop CF a baby has to inherit the faulty gene from both parents. About one in 25 people in the UK is a carrier of the CF gene.
Inheritance is autosomal recessive. This means if both parents are carriers there's a one in four chance their child will have CF and a two in four chance their child will be a carrier but not have the disease. There's a one in four chance that their child will neither have CF nor be a carrier.
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What are the symptoms?
Common problems people with CF experience include:
The life expectancy of CF patients continues to increase. About 75 per cent of affected children survive to young adulthood and the average life expectancy is between 30 and 40.
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Can it be prevented?
As yet there's no cure for CF or any way of preventing it. However, since the faulty gene has been identified, much work and research is being done to try to find ways to either repair or replace this gene through gene therapy.
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How is it diagnosed?
All newborn babies are screened for cystic fibrosis. Antenatal tests for the disease are also available.
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What's the treatment?
Treatment can help people to live with cystic fibrosis. It can also prevent or reduce long-term damage from infection and other complications.
High-energy foods, enzyme supplements, and vitamin and mineral supplements help a person with CF to get the nutrients they need. Regular exercise is important to keep the body fit and healthy.
Daily physiotherapy and breathing exercises help to keep the body healthy and to prevent excessive build up of mucus in the lungs.
Antibiotics and other medicines are used to control lung infections and inflammation. If respiratory failure occurs, a lung transplant may be necessary.
CF is an inherited condition affecting the glands that produce body fluids or secretions.
In CF, these secretions are stickier and thicker than normal. This hinders the functioning of important organs, such as the lungs and digestive system.
Top
What causes it?
The exact cause of CF is a single faulty gene found on chromosome 7, which controls salt and water movement in and out of cells within the body. To develop CF a baby has to inherit the faulty gene from both parents. About one in 25 people in the UK is a carrier of the CF gene.
Inheritance is autosomal recessive. This means if both parents are carriers there's a one in four chance their child will have CF and a two in four chance their child will be a carrier but not have the disease. There's a one in four chance that their child will neither have CF nor be a carrier.
Top
What are the symptoms?
Common problems people with CF experience include:
- Recurrent and severe chest infections
- Malabsorption and failure to thrive
- Passing of large, foul-smelling motions
- Diabetes
- Liver failure
- Infertility
The life expectancy of CF patients continues to increase. About 75 per cent of affected children survive to young adulthood and the average life expectancy is between 30 and 40.
Top
Can it be prevented?
As yet there's no cure for CF or any way of preventing it. However, since the faulty gene has been identified, much work and research is being done to try to find ways to either repair or replace this gene through gene therapy.
Top
How is it diagnosed?
All newborn babies are screened for cystic fibrosis. Antenatal tests for the disease are also available.
Top
What's the treatment?
Treatment can help people to live with cystic fibrosis. It can also prevent or reduce long-term damage from infection and other complications.
High-energy foods, enzyme supplements, and vitamin and mineral supplements help a person with CF to get the nutrients they need. Regular exercise is important to keep the body fit and healthy.
Daily physiotherapy and breathing exercises help to keep the body healthy and to prevent excessive build up of mucus in the lungs.
Antibiotics and other medicines are used to control lung infections and inflammation. If respiratory failure occurs, a lung transplant may be necessary.
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