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International sanctions on Iran have been lifted after a watchdog confirmed it had complied with a deal designed to prevent it developing nuclear weapons.
The EU foreign policy chief, Federica Mogherini, said the deal would contribute to improved regional and international peace and security.
The landmark deal between Iran and world powers was agreed last July.
Lifting the sanctions will unfreeze billions of dollars of assets and allow Iran's oil to be sold internationally.
The international nuclear watchdog, the IAEA, said its inspectors had verified that Tehran had taken the required steps.
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As part of the deal, Iran had to drastically reduce its number of centrifuges and dismantle a heavy-water reactor near the town of Arak, both of which could be used in creating nuclear weapons.
Image copyright EPA Image caption Iran has been subject to crippling economic sanctions from the US and the EU Iran has always maintained its nuclear programme is peaceful, but opponents of the deal - such as some US Republicans - say it does not do enough to ensure the country cannot develop a nuclear bomb.
The US Secretary of State John Kerry has ordered that US nuclear-related economic sanctions against Iran be lifted.
Speaking in Vienna where he had been holding talks with his Iranian counterpart, Mr Kerry said Iran had "undertaken significant steps" which many people "doubted would ever come to pass".
The response
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Media captionThe EU foreign policy chief, Federica Mogherini, announced the lifting of sanctions in accordance with the deal "as Iran has fulfilled its commitment". "I thank God for this blessing and bow to the greatness of the patient nation of Iran" - Iranian President Hassan Rouhani on Twitter
"Today, as a result of the actions taken since last July, the United States, our friends and allies in the Middle East, in the entire world are safer because the threat of a nuclear weapon has been reduced" - US Secretary of State John Kerry
"Even after signing the nuclear deal, Iran has not relinquished its ambition to obtain nuclear weapons, and continues to act to destabilise the Middle East and spread terror throughout the world while violating its international commitments" - Israeli Prime Minister Benjamin Netanyahu
"Today, the Obama administration will begin lifting economic sanctions on the world's leading state sponsor of terrorism" - US Republican House Speaker Paul Ryan in a statement
"Years of patient and persistent diplomacy, and difficult technical work, have borne fruit as we now implement the deal" - British Foreign Secretary Philip Hammond
Earlier on Saturday it emerged that Iran had released Washington Post reporter Jason Rezaian and three other Iranian-American prisoners in an apparent prisoner swap with the United States.
Rezaian, 39, was jailed on charges, including espionage, last November.
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Media captionThe deal will last from 10 to 15 years but the IAEA inspections will continue The US said it was offering clemency to seven Iranians being held in the US for sanctions violation.
Mr Kerry said said he was "very happy to say that as we speak five Americans have been released from custody and they should be on their way home to their families shortly".
A fifth American, Matthew Trevithick, was also released on Saturday.
President Barack Obama would give more details of the releases later, Mr Kerry said.
The IAEA said it had installed a device at the Natanz plant to monitor Iran's uranium enrichment activities in real time, in order to verify that uranium enrichment levels were kept at up to 3.67% as agreed in the deal with world powers.
The organisation's head, Yukiya Amano, is to visit Tehran on Sunday for meetings with President Rouhani and other officials.
What is the nuclear deal?
In July 2015, Iran agreed a landmark nuclear deal with six world powers to limit its sensitive nuclear activities for more than a decade in return for the lifting of crippling sanctions. The US is confident the agreement will prevent Iran from obtaining a nuclear weapon. Iran says it has the right to nuclear energy - and stresses that its nuclear programme is for peaceful purposes only.
What does Iran stand to gain?
The sanctions have cost Iran more than more than $160bn (£102bn) in oil revenue since 2012 alone. Once they are lifted, the country will be able to resume selling oil on international markets and using the global financial system for trade. Iran has the fourth largest oil reserves in the world and the energy industry is braced for lower prices. Iran will also be able to access more than $100bn in assets frozen overseas.
What lifting Iran sanctions means for world markets
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Iran nuclear issue
Background
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The EU foreign policy chief, Federica Mogherini, said the deal would contribute to improved regional and international peace and security.
The landmark deal between Iran and world powers was agreed last July.
Lifting the sanctions will unfreeze billions of dollars of assets and allow Iran's oil to be sold internationally.
The international nuclear watchdog, the IAEA, said its inspectors had verified that Tehran had taken the required steps.
Iran nuclear deal: Key details
Iran nuclear crisis: Six key points
Will Iran now get a McDonald's?
As part of the deal, Iran had to drastically reduce its number of centrifuges and dismantle a heavy-water reactor near the town of Arak, both of which could be used in creating nuclear weapons.
Image copyright EPA Image caption Iran has been subject to crippling economic sanctions from the US and the EU Iran has always maintained its nuclear programme is peaceful, but opponents of the deal - such as some US Republicans - say it does not do enough to ensure the country cannot develop a nuclear bomb.
The US Secretary of State John Kerry has ordered that US nuclear-related economic sanctions against Iran be lifted.
Speaking in Vienna where he had been holding talks with his Iranian counterpart, Mr Kerry said Iran had "undertaken significant steps" which many people "doubted would ever come to pass".
The response
Jump media player
Media player help
Out of media player. Press enter to return or tab to continue.
Media captionThe EU foreign policy chief, Federica Mogherini, announced the lifting of sanctions in accordance with the deal "as Iran has fulfilled its commitment". "I thank God for this blessing and bow to the greatness of the patient nation of Iran" - Iranian President Hassan Rouhani on Twitter
"Today, as a result of the actions taken since last July, the United States, our friends and allies in the Middle East, in the entire world are safer because the threat of a nuclear weapon has been reduced" - US Secretary of State John Kerry
"Even after signing the nuclear deal, Iran has not relinquished its ambition to obtain nuclear weapons, and continues to act to destabilise the Middle East and spread terror throughout the world while violating its international commitments" - Israeli Prime Minister Benjamin Netanyahu
"Today, the Obama administration will begin lifting economic sanctions on the world's leading state sponsor of terrorism" - US Republican House Speaker Paul Ryan in a statement
"Years of patient and persistent diplomacy, and difficult technical work, have borne fruit as we now implement the deal" - British Foreign Secretary Philip Hammond
Earlier on Saturday it emerged that Iran had released Washington Post reporter Jason Rezaian and three other Iranian-American prisoners in an apparent prisoner swap with the United States.
Rezaian, 39, was jailed on charges, including espionage, last November.
Jump media player
Media player help
Out of media player. Press enter to return or tab to continue.
Media captionThe deal will last from 10 to 15 years but the IAEA inspections will continue The US said it was offering clemency to seven Iranians being held in the US for sanctions violation.
Mr Kerry said said he was "very happy to say that as we speak five Americans have been released from custody and they should be on their way home to their families shortly".
A fifth American, Matthew Trevithick, was also released on Saturday.
President Barack Obama would give more details of the releases later, Mr Kerry said.
The IAEA said it had installed a device at the Natanz plant to monitor Iran's uranium enrichment activities in real time, in order to verify that uranium enrichment levels were kept at up to 3.67% as agreed in the deal with world powers.
The organisation's head, Yukiya Amano, is to visit Tehran on Sunday for meetings with President Rouhani and other officials.
What is the nuclear deal?
In July 2015, Iran agreed a landmark nuclear deal with six world powers to limit its sensitive nuclear activities for more than a decade in return for the lifting of crippling sanctions. The US is confident the agreement will prevent Iran from obtaining a nuclear weapon. Iran says it has the right to nuclear energy - and stresses that its nuclear programme is for peaceful purposes only.
What does Iran stand to gain?
The sanctions have cost Iran more than more than $160bn (£102bn) in oil revenue since 2012 alone. Once they are lifted, the country will be able to resume selling oil on international markets and using the global financial system for trade. Iran has the fourth largest oil reserves in the world and the energy industry is braced for lower prices. Iran will also be able to access more than $100bn in assets frozen overseas.
What lifting Iran sanctions means for world markets
Share this story About sharing
Iran nuclear issue
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- Will Iran nuclear deal make the Middle East a less safe place?
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- Iran nuclear agreement: A good deal, for now?
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Background
- What are the sanctions on Iran?
30 March 2015
- Iran's key nuclear sites
14 July 2015
- Guide: Nuclear fuel cycle
- Iran country profile
10 November 2015
- How Iran is ruled
9 June 2009
- Video Need to Know: Iran's leadership
18 May 2013
- US-Iran relations: A brief guide
24 November 2014
Video and audio
- Video Iran negotiations in 90 seconds
30 June 2015
- Video Iran sanctions: Voices from Tehran
10 July 2015
- Video US-Iran relations: A brief guide
18 June 2014
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